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AIMS: Main - To research the scientific activity of sorafenib tosylate and fulvestrant, as determined by a 4-month progression-free survival rate, in sufferers with hormone receptor-positive regionally superior or metastatic breast cancer that progressed after prior remedy with an aromatase inhibitor. The fee-effectiveness evaluation outcomes confirmed lenvatinib remedy dominated sorafenib, because of the mean ICER falling within the fourth quadrant, as lenvatinib was more effective (measured by QALYs) and less expensive in contrast with sorafenib for uHCC therapy in Japan.
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