Why is it important to focus on the importance of cold chain transport for vaccines? |
Posted: May 24, 2023 |
1. Understanding vaccines After vaccination, human rabbit immune cells secrete antibodies, which bind with pathogens in the blood and are then secreted or perhaps processed by other cells and then processed into small molecules before being excreted. As the antibodies bind to the microorganisms early, they block the microorganisms from binding to the cells, so that we will not be infected by the microorganisms and therefore we will not get sick.
The chemical substance of vaccines is proteins or consists of complexes of lipids, polysaccharides and proteins, which are subject to the effects of light and heat, which can denature proteins and dissolve polysaccharides and lose their immunological characteristics. In addition, vaccines contain a number of adjuvant components, like adjuvants, preservatives, stabilisers, etc., and are subject to very strict requirements for their delivery. Thus, vaccines are temperature sensitive.
2. Effects of vaccine chain breaks on humans
As biological products, vaccines are sensitive to temperature and can be affected by high or low temperatures. The cold chain is particularly important in order to ensure the stability and antigenicity of the vaccine, which has to go through several stages of distribution, delivery and storage from the time of production to the time of vaccination.
Generally speaking, vaccines need to be stored below 8?, while specific requirements are subject to the instructions. In order to ensure low temperatures, there is also a lot of specialized equipment in the safe transport of vaccines, including cryogenic cold storage, ice racks for quick freezing, general cold storage, refrigerated trucks, refrigerators, refrigerated backpacks, etc.
If the vaccine is left out of the cold chain, it may be weakened or ineffective and the effect of the vaccination will be greatly reduced. For example, the rabies vaccine is designed to save lives, but if the vaccine is weakened or expired, it will increase the probability of rabies virus infection and will not have the effect of saving lives, which is very serious. This is also true for other vaccines, which may have other side effects if they are completely ineffective. Vaccine failure itself increases the likelihood of infection from related infectious diseases.
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