FSGS is an autoimmune disease, and the main cause is glomerular epithelia has been damaged. Over time, the damage to the kidneys may lead to kidney failure, or end-stage renal disease (ESRD). About half of FSGS patients who do not respond to steroids go into ESRD each year, requiring kidney transplant. However, within hours to weeks after a transplant, the disease returns in approximately 30%~40% of patients. So, it is wise for patients to find a better thorough treatment.
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