Corticosteroid, a varied catalyst.
Corticosteroid 11 Beta Dehydrogenase Isozyme 1 (11 Beta Hydroxysteroid Dehydrogenase 1 or Short Chain Dehydrogenase/Reductase Family 26C Member 1 or HSD11B1 or EC 1.1.1.146) - 11beta-hydroxysteroid dehydrogenase type 1 is an NADPH-dependent enzyme highly expressed in key metabolic tissues including liver, adipose tissue, and the central nervous system. In these tissues HSD11B1 reduces cortisone to the active hormone cortisol that activates glucocorticoid receptors. This enzyme plays an important role in obesity and insulin resistance.
Covers products from therapy areas: Metabolic Disorders, Central Nervous System, Ophthalmology, Cardiovascular, Immunology and Musculoskeletal Disorders which include indications Type 2 Diabetes, Alzheimers Disease, Dementia Associated With Alzheimers Disease, Obesity, Ocular Hypertension, Open-Angle Glaucoma, Cushings Syndrome, Diabetic Complications, Inflammation, Intracranial Hypertension, Metabolic Syndrome, Muscle Atrophy, Myocardial Infarction and Post-Traumatic Stress Disorder (PTSD). It is built using data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.
Scope - Provides a snapshot of the global therapeutic landscape for Corticosteroid 11 Beta Dehydrogenase Isozyme 1 - Reviews Corticosteroid 11 Beta Dehydrogenase Isozyme 1 targeted therapeutics under development by companies and universities/research institutes. - Covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages. - Features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities. Reasons to buy - Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies. - Identify the use of drugs for target identification and drug repurposing
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