Hemophilia Market Trends, Growth Rate, Consumption By Regional Data And Forecast 2022-2031 |
Posted: August 10, 2022 |
The Hemophilia market is expected to witness a CAGR of 5.9% during the forecast period (2022 - 2031). They should take measures to keep their blood pressure in check and follow general guidelines to keep their immune system strong. Moreover, it is impossible to estimate how many patients with hemophilia will become infected, and whether their factor deficiency and its treatment can influence the manifestations of the infection, its natural course, treatment, and consequences. In December 2020, the World Federation of Hemophilia (WFH), European Association for Haemophilia and Allied Disorders (EAHAD), European Haemophilia Consortium (EHC), and U.S. National Hemophilia Foundation (NHF) issued a joint COVID-19 vaccination guidance for people with bleeding disorders. It stated that people with bleeding disorders were not at greater risk of contracting COVID-19 or developing a severe form of the disease. Thus, people with these disorders were more likely to get themselves treated after they get vaccinated. According to the World Federation of Hemophilia 2019 global survey report, in 2019, there were 31,997 people diagnosed with hemophilia B, around 5,749 people with unknown hemophilia types, and around 49,083 people were diagnosed for other bleeding disorders. Moreover, according to a study report by Allison Inserro published in the American Journal of Managed Care 2019, the prevalence of hemophilia B at birth is 5 cases for all severities of hemophilia B (per 100,000 males) and 1.5 cases for severe hemophilia B (per 100,000 males). For those born with hemophilia, the chances of living a life of normal duration and quality is reduced by 64% in the upper-middle-income countries, 77% in middle income, and up to 93% in low-income countries. This indicates reduction in quality of life due to hemophilia B, increasing the need for effective hemophilia treatment, which is expected to drive the market in the coming years. This is a rare genetic bleeding disorder projected that affected around 157,517 people worldwide in 2019. The key medication to treat hemophilia A is concentrated FVIII product, also known as clotting factor. The recombinant factor products that are developed in a laboratory using DNA technology impede the use of human-derived pools of donor-sourced plasma. Due to the advances in recombinant protein engineering and the introduction of gene therapy and novel strategies to target the coagulation cascade. In 2018, Roche announced the approval of “Hemlibra” for expanded use in the routine prophylaxis of bleeding episodes in patients with hemophilia A without factor VIII (FVIII) inhibitors. The Takeda Pharmaceutical Company Limited offers "ADVATE“, which is used to replace clotting factor (factor VIII or antihemophilic factor) is missing among people with hemophilia A (also called “classic” hemophilia). Furthermore, according to the National Clinical Registry (NCT), as of August 11, 2020, worldwide, there were about 139 ongoing clinical trials across different phases of development for hemophilia A (HA). Moreover, the increasing demand for advanced products for the diagnosis and treatment of hemophilia is projected to trigger the growth of this segment in the forecast period. The United States is the largest market in the region. According to the World Federation of Hemophilia 2018 report, in 2018, there were about 17,757 people diagnosed with hemophilia in the United States. Furthermore, in 2019, the number of people with hemophilia in the United States increased to about 20,000 individuals, as per NHF (National Health Federation). In the United States, agencies, like hemophilia Association of America, generally offers continuous treatment for patients by introducing different co-pay initiatives. This is further expected to balance the expenditures for patients and assist them in providing access to new products. In the United States, the BioMarin company is conducting Phase III clinical trial with valoctocogene roxaparvovec (BMN 270) to assess the efficacy of BMN 270 in the treatment of hemophilia A. Therefore, advancements in the gene therapy and novel strategies to target the coagulation factors is expected to drive the market in the near future. In the United States, Genzyme Corporation offers "ALPROLIX" (Coagulation Factor IX (Recombinant), Fc Fusion Protein), an injectable medicine used to help control and prevent bleeding in people with hemophilia B. Thus, the increasing research and development in the development of new effective therapies, along with the rising prevalence of hemophilia in the United States, is expected to drive the market over the forecast period.
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