Fmoc PNA Monomers |
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Fmoc is used as the protecting group of a-amino of amino acid. Its advantage is that it is stable under acidic conditions which is not affected by trifluoroacetic acid (TFA) and other reagents, and can be deprotected by mild alkali treatment. At the same time, the Fmoc method has fewer side reactions, high yield, and the Fmoc group itself has characteristic UV absorption, which is easy to monitor and control the reaction.
https://aapep.bocsci.com/pna-monomers/fmoc-pna-monomers-4631.html |
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