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When coping with Type 2 diabetes, healthcare companies regularly consider numerous medicinal drug alternatives to optimize affected person consequences. Two prominent choices within the landscape of diabetes treatment are Ozempic (semaglutide) and Mounjaro (tirzepatide) injection in Dubai UAE . Both are injectable medicines that fall underneath the category of GLP-1 receptor agonists, but they have got awesome mechanisms of motion, efficacy profiles, and aspect consequences. This article explores the important thing differences and similarities among Ozempic and Mounjaro to help sufferers and healthcare professionals make informed choices.
Overview of Ozempic and Mounjaro
Ozempic
Ozempic is a GLP-1 receptor agonist synthetic via Novo Nordisk. It was accepted by way of the FDA in December 2017 for the remedy of Type 2 diabetes and has gained recognition for its weight loss benefits.
Mechanism of Action: Ozempic mimics the motion of the GLP-1 hormone, that's concerned in glucose metabolism. It will increase insulin secretion in response to excessive blood sugar ranges, inhibits glucagon launch, and slows gastric emptying, main to reduced appetite and elevated feelings of fullness.
Indications: Ozempic is indicated for improving glycemic control in adults with Type 2 diabetes and can also assist in weight management when blended with a reduced-calorie food regimen and exercise.
Dosing: The normal dosing routine begins at 0.25 mg as soon as weekly for four weeks, followed by way of an boom to 0.5 mg or 1 mg, with a maximum dose of two mg relying at the affected person’s reaction.
Mounjaro
Mounjaro, developed by way of Eli Lilly, is a newer remedy that works as a dual GLP-1 and GIP (glucose-structured insulinotropic polypeptide) receptor agonist. It become authorized via the FDA in May 2022 for Type 2 diabetes treatment.
Mechanism of Action: Mounjaro turns on both GLP-1 and GIP receptors, enhancing insulin secretion, growing insulin sensitivity, and selling weight loss. This twin motion facilitates modify blood sugar tiers more effectively than medications concentrated on handiest GLP-1.
Indications: Mounjaro is also indicated for Type 2 diabetes management and has shown enormous ability for weight loss.
Dosing: Mounjaro starts offevolved at 2.Five mg as soon as weekly and can be extended primarily based on effectiveness and tolerability, attaining a maximum dose of 15 mg.
Key Comparisons Between Ozempic and Mounjaro
1. Mechanism of Action
The number one distinction among Ozempic and Mounjaro lies in their mechanisms of action. While both medications stimulate GLP-1 receptors, Mounjaro’s twin action—stimulating each GLP-1 and GIP—affords a greater complete technique to managing blood glucose levels and facilitating weight loss.
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