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Millions of guys have tried using Cialis, Viagra or Levitra from the moment they were first offered the marketplace. However, few of these users, if any,acknowledged the danger of acquiring skin cancer as a result of that usage. A relatively new study published in the Journal of the American Medical Association (JAMA) discovered that males who used these drugs were associated with an increased threat of acquiring melanoma, despite accounting for other risks presented. This research study involved more than 20,000 males throughout a period of ten years and discovered a near doubling of relative threat as compared with non-users. Due to the mechanism of how the drug works, Levitra and Cialis are believed to expose users to the precise threats as Viagra in terms of increased vulnerability to cancer malignancy. They do so by preventing the phosphodiesterase 5 (PDE5). Speculative research studies have shown that this consequently enhances tumor cell invasivene